Hair zinc level in Down syndrome.

نویسندگان

  • Ayse Yenigun
  • Ferda Ozkinay
  • Ozgur Cogulu
  • Canan Coker
  • Nurten Cetiner
  • Gonca Ozden
  • Oguz Aksu
  • Cihangir Ozkinay
چکیده

Immunological, endocrinological, and haematological abnormalities are relatively common in people with Down syndrome (Cuadrado & Barrena, 1996; Decoq & Vincker, 1995; Hestnes et al., 1991; Sustrova & Strbak, 1994; Nespoli, Burgio, Ugazio & Maccario, 1993; Kempski, Chessells & Reeves, 1997; Kivivuori, Rajantie, & Siimes, 1996; David et al., 1996; Gjertson, Sturm & Berger, 1999). Zinc is one of the elements that act in the maintenance of normal function of these systems. This study was designed to investigate zinc levels in children with Down syndrome. Zinc levels were measured in hair using atomic absorption spectrophotometry. The hair zinc level of 19 children with Down syndrome was compared with the zinc level of 11 typically developing children. Hair zinc levels were found to be significantly lower (p < .05) in those with Down syndrome (average 95.18 +/- 56.10 ppm) than in the typically developing children (average 208.88 +/- 152.37 ppm). Some of the problems experienced by children with Down syndrome may be due to these low zinc levels, but further research is required to confirm these results, and to establish any correlation with these problems.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

میزان عنصر روی موجود در موی کودکان مبتلا به سندرم‌داون، فلج مغزی، ماکروسفالی، میکروسفالی و هیدروسفالی

AbstractObjectives: The purpose of this survey was to compare the amount of zinc concentration between normal children and the children suffering from Down syndrome, cerebral palsy, micro-macrocephaly, and hydrocephaly in Iran. The correlation between zinc concentration and the spoken syndromes was further assessed. Method: In the present study, the hair sam-ples were used to estimate zinc conc...

متن کامل

Zinc Concentration in Thalassemic Patients Hair

ABSTRACT Thalassemia is a common genetic diseaes. Due to repeated blood transfuion and increasing iron load, deferoxamin is used in this illness. One of it's adverse effect is binding to zinc element, Regarding to effects of zinc on growth and development, when the patient's zinc hair was less than healthy person, it is concluded that with administration of zinc element, There was significant ...

متن کامل

Comparison of Zn, Cu, and Fe Content in Hair and Serum in Alopecia Areata Patients with Normal Group

Background. Alopecia areata (AA) is an autoimmune condition, in which hair is lost from some areas of the body. Though its etiopathogenesis is not fully understood, there are claims that imbalance of trace elements may trigger the onset of AA, by distorting immune functions. In this study, we tried to investigate the relationship between AA and iron, zinc, and copper levels of serum and hair. M...

متن کامل

Determination of the sensitivity and secificity of hypertrophy of hyponychium as a new diagnodtic sing in down syndrome

down syndrome is the most common known chromosomal disorder in man.this syndrome has many sings and symptoms which are variable in frequency.taking all the signs and symproms in to consideration,diagnosis of down syndrome is not a difficult task-however in the past it was difficult to diagnose this syndrome based on a single clinical sign,until  hypertrophy of hyponichium was first introduced b...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Down's syndrome, research and practice : the journal of the Sarah Duffen Centre

دوره 9 2  شماره 

صفحات  -

تاریخ انتشار 2004